A Fully Integrated Tumor-on-a-Chip Platform
A next-generation microphysiologic system that preserves the native tumor microenvironment to generate scalable, clinically actionable data.
From patient-derived tissue to functional response profiling, our platform transforms preclinical research into translational clarity.
Engineering Precision Oncology at Physiologic Scale
Encapsulate’s biochip platform is built to maintain the architectural and cellular complexity of a patient tumor.
By creating hundreds of replicates from the original tissue and preserving the microenvironmental integrity, the platform enables accurate biological behavior in a highly controlled setting.
Microfluidic Precision
Customizable channels enable precise control over perfusion, nutrient gradients, and drug exposure kinetics.
High-Throughput Capacity
Customizable channels enable precise control over perfusion, nutrient gradients, and drug exposure kinetics.
Translational Scalability
Engineered for high reproducibility and seamless integration into clinical workflows.
Patient-Derived Tumor Models
Our platform utilizes 3D tumor organoids derived directly from patients. These robust models preserve the clinically relevant features, genomic alterations, and physical architecture of the original cancer.
Human-Relevant Biology
Surpasses traditional 2D cultures by preserving the native tumor microenvironment, including stromal cells, extracellular matrix, and immune cell interactions.
Functional Drug Testing
Enables rapid evaluation of therapeutic responses across regimens, varying doses, and combination therapies.
Inter-Patient Variability
Captures diverse disease biology to provide translationally meaningful insights that reflect real-world patient populations.
Clinically Anchored
Aligns with the National Institute of Health (NIH) and National Cancer Institute (NCI) translational initiatives that emphasize standardized organoid platforms and reduced reliance on animal testing.
Automated Microfluidic Control
Biological complexity requires rigorous environmental consistency. Encapsulate integrates automated microfluidics to enable precise and reproducible manipulation of the tumoroid microenvironment, supporting standardized execution of complex biological assays.
Precision Fluidics
An integrated pump-driven system enables highly controlled delivery of media, reagents, and therapeutic compounds directly into the biochip environment.
Programmable Dosing
Automated flow allows for customizable schedules, such as continuous perfusion or time-controlled pulse exposure, to accurately model clinical pharmacokinetics.
Standardized Workflows
Automation drastically reduces operator-dependent variability and ensures consistent experimental execution for translational research and drug development.
From Complex Biology to Interpretable Datasets
Encapsulate transforms dynamic biological experiments into reproducible and interpretable datasets. Our integrated digital framework links imaging, metadata, and environmental conditions to build a structured foundation for advanced response modeling and future machine learning applications.
Quantitative Phenotyping
High resolution imaging pipelines objectively quantify phenotypic responses, capturing precise data on tumor growth, viability, and morphology.
Advanced Tumor Tracking
The structured data infrastructure directly supports the integration of AI/ML development for predictive modeling and longitudinal tumor tracking.
Clinician Ready Reporting
Generates structured profiles that summarize experimental conditions and rank candidate therapies based on quantitative efficacy metrics for decision-making.
Validated in Space
Built for robust performance, our automated microfluidic biochip platform is engineered to operate reliably in space.
Orbital Deployment
Fully operational in terrestrial labs and on space-based research platforms, including the International Space Station.
Microgravity Research
Allows researchers to explore how altered physical conditions affect tumor biology, disease progression, and therapeutic response.